1 standard vape pod does not directly equal 20 packs of cigarettes in terms of nicotine content, but it can contain nicotine equivalent to a pack of cigarettes. A JUUL pod, for Much Nicotine Is One Vape Can Equal 20 Packs Of Cigarettes. That's How Much Nicotine Some E Cigar How Many Cigarettes Are In One Vape Battery How Much Nicotine Is in a Vape Compared to Cigarettes? Poison center warns of JUUL use; 1 pod has 5% nicotine or 1 pack of 20 cigarettes