Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Figure 4 Vitamin D deficiency as a potential risk factor for accelerated aging, impaired hippocampal neurogenesis and cognitive decline: a role for Wnt β catenin signaling Aging Neuron glia interaction through Serotonin BDNF NGFR axis enables regenerative neurogenesis in Alzheimer's model of adult zebrafish brain PLOS Biology Dihexa Peptide Dallas Cognitive Enhancement & Brain Health
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dihexa promotes neurogenesis The Role of Neurogenesis in Neurodegenerative Diseases: Mechanisms and Interventions