Hepatocyte Growth Factor MET Activator Rescues Working Memory Deficits after Repeated Mild Traumatic Brain Injury Katelyn A. Martino, Arush Nakhre, Renee M. Demarest, David M. Devilbiss, 2025 Dihexa is an experimental cognitive peptide that may help the brain build stronger connections between neurons instead of just temporarily boosting neurotransmitters like many nootropics do. It works through the HGF c Met pathway, Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted HGF c Met 1 integrin signalling axis induces tunneling nanotubes in A549 lung adenocarcinoma cells Life Science Alliance