An overview of the c MET signaling pathway Shawna Leslie Organ, Ming Sound Tsao, 2011 What if neuroplasticity research targeted the HGF c Met pathway? Dihexa (PNB 0408) is an angiotensin IVderived peptide studied in preclinical models for its role in synaptogenesis and cognitive signaling mechanisms. Human data remains limited. Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Therapeutic targeting of HGF c Met pathway. c Met pathway inhibition Download Scientific Diagram