Circulating acetaminophen metabolites are toxicokinetic biomarkers of acute liver injury Vliegenthart 2017 Clinical Pharmacology & Therapeutics Wiley Online Library Acetaminophen (brand name Tylenol) is found in hundreds of prescription and over the counter medicines. Taking more than directed can cause serious health problems. Always read medicine labels and follow the instructions carefully. If Ferroptosis driven by radical oxidation of n 6 polyunsaturated fatty acids mediates acetaminophen induced acute liver failure Cell Death & Disease In vivo upstream factors of mouse hepatotoxic mechanism with sustained hepatic glutathione depletion: Acetaminophen metabolite erythrocyte adducts and splenic macrophage generated reactive oxygen species ScienceDirect